Forced Degradation and Stability Indicating Studies for Clomifene Citrate Tablet

Pharmaceutical medications must be stable to preserve their efficacy and safety over the period of shelf lives. Studies on force degradation are crucial for identifying probable pathways extreme stresses that may lead breakdown pharmaceutical product. This report offers a thorough analysis tests performed Clomifene citrate tablets. Evaluation effects several stress factors, including temperature, humidity, light, mechanical forces, stability clomifene is main goal. To replicate actual storage handling situations, study used testing criteria specified by International Conference Harmonization (ICH). According study, temperature humidity have biggest roles in In this article FDS was using stainless-steel column (250 mm x 4.6 mm) packed with Butylsilane C4 (5µm) L26, detector 233nm, mobile phase; Phase prepared mixing 550 volumes methanol, 450 water 3 triethylamine. Then adjust pH 2.5 phosphoric acid. Flow rate; 1 mL/mint. The quantification hyphenation instrumental were successfully accomplished developed method.